| 4 |  Donald Trump@realDonaldTrump | President of the United States (2017–2021, 2025–present) | 111.7M | |
| 5 |  Narendra Modi@narendramodi | Prime Minister of India (2014–present) | 107.1M | |
| 6 |  Rihanna@rihanna | Musician and businesswoman | 98.5M | |
| 7 |  NASA@NASA | Space agency | 92.3M | |
| 8 |  Justin Bieber@justinbieber | Musician | 91.7M | |
| 9 |  Katy Perry@katyperry | Musician | 89.6M | |
| 10 |  Taylor Swift@taylorswift13 | Musician | 83.5M | |
| 11 |  Lady Gaga@ladygaga | Musician and actress | 75M | |
| 12 |  Virat Kohli@imVkohli | Cricket player | 72.7M | |
| 13 |  Kim Kardashian@KimKardashian | Television personality and businesswoman | 70.7M | |
| 14 |  YouTube@YouTube | Online video sharing platform | 68.8M | |
| 15 |  Neymar@neymarjr | Football player | 65.7M | |
| 16 |  Bill Gates@BillGates | Businessman and philanthropist | 64.8M | |
| 17 |  Ellen DeGeneres@TheEllenShow | Comedian and former television host | 62.3M | |
| 18 |  Selena Gomez@selenagomez | Musician and actress | 62.6M | |
| 19 |  CNN@CNN | News channel | 61.8M | |
| 20 |  X (formerly Twitter)@X | Operator of platform | 60.7M | |
| 21 |  CNN Breaking News@cnnbrk | News channel | 60M | |
| 22 |  ESPN@espn | Sports channel | 58.6M | |
| 23 |  PMO India@PMOIndia | Office of the Prime Minister of India | 58.3M | |
| 24 |  LeBron James@KingJames | Basketball player | 54.6M | |
| 25 |  The New York Times@nytimes | Newspaper | 53.8M | |
| 26 |  UEFA Champions League@ChampionsLeague | Football league | 53M | |
| 27 |  BBC Breaking News@BBCBreaking | News channel | 50.1M | |
| 28 |  Real Madrid CF@realmadrid | Football club | 49.5M | |
| 29 |  Justin Timberlake@jtimberlake | Musician and actor | 47.7M | |
| 30 |  BTS@BTS_twt | Musicians | 47.4M | |
| 31 |  NBA@NBA | Basketball league | 47M | |
| 32 |  FC Barcelona@FCBarcelona | Football club | 46.8M | |
| 33 |  Premier League@premierleague | Football league | 46.1M | |
| 34 |  Demi Lovato@ddlovato | Musician and actress | 45.8M | |
| 35 |  Shakira@shakira | Musician | 45.4M | |
| 36 |  BTS@bts_bighit | Musicians | 45.3M | |
| 37 |  Amitabh Bachchan@SrBachchan | Actor | 44.7M | |
| 38 |  PlayStation@PlayStation | Video gaming brand | 44.5M | |
| 39 |  Akshay Kumar@akshaykumar | Actor | 44.2M | |
| 40 | | Musician and actress | 43.6M | |
| 41 |  Britney Spears@britneyspears | Musician | 43M | |
| 42 |  Jimmy Fallon@jimmyfallon | Comedian and television host | 42.9M | |
| 43 |  BBC World News@BBCWorld | News channel | 42.3M | |
| 44 |  Salman Khan@BeingSalmanKhan | Actor | 42.2M | |
| 45 |  SportsCenter@SportsCenter | Sports channel | 42.1M | |
| 46 |  SpaceX@SpaceX | Space agency | 41.8M | |
| 47 |  Shah Rukh Khan@iamsrk | Actor | 40.1M | |
| 48 |  Kylie Jenner@KylieJenner | Social media personality and businesswoman | 39.5M | |
| 49 |  Sachin Tendulkar@sachin_rt | Former cricket player | 39M | |
| 50 |  Manchester United F.C.@ManUtd | Football club | 38.2M | |
